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Loss of Dgcr8-mediated microRNA expression in the kidney results in hydronephrosis and renal malformation

BACKGROUND: Small non-coding RNA molecules (miRNAs) play a pivotal role in regulating gene expression in development. miRNAs regulate key processes at the cellular level and thereby influence organismal and tissue development including kidney morphogenesis. A miRNA molecule is initially synthesized...

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Detalles Bibliográficos
Publicado en:BMC Nephrol
Autores principales: Bartram, Malte P, Dafinger, Claudia, Habbig, Sandra, Benzing, Thomas, Schermer, Bernhard, Müller, Roman-Ulrich
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445526/
https://ncbi.nlm.nih.gov/pubmed/25881298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-015-0053-1
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