Secretion of apolipoprotein B-containing lipoproteins from HeLa cells is dependent on expression of the microsomal triglyceride transfer protein and is regulated by lipid availability.

To elucidate the role of the microsomal triglyceride transfer protein (MTP) in lipoprotein assembly, MTP and apolipoprotein B-53 (apoB 53; the N-terminal 53% of apoB) were expressed in HeLa cells. The results showed that apoB-53 could be expressed in HeLa cells with or without expression of MTP. In...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Gordon, D A, Jamil, H, Sharp, D, Mullaney, D, Yao, Z, Gregg, R E, Wetterau, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052632/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7628
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