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Selective Membrane Toxicity of the Polyene Antibiotics: Studies on Lecithin Membrane Models (Liposomes)

In the absence of sterol, amphotericin B at 5 × 10(−6) M caused maximum marker release from the saturated dipalmitoyl lecithin liposomes, minimum release from the unsaturated dioleoyl lecithin liposomes, and an in-between response from egg lecithin liposomes. Nystatin at 2.5 to 4.0 × 10(−5) M induce...

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Autors principals: Hsuchen, Chuen-Chin, Feingold, David S.
Format: Artigo
Idioma:Inglês
Publicat: 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC444548/
https://ncbi.nlm.nih.gov/pubmed/4758835
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