Coherence analysis discriminates between retroviral integration patterns in CD34(+) cells transduced under differing clinical trial conditions

Unequivocal demonstration of the therapeutic utility of γ-retroviral vectors for gene therapy applications targeting the hematopoietic system was accompanied by instances of insertional mutagenesis. These events stimulated the ongoing development of putatively safer integrating vector systems and an...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Principais autores: Hallwirth, Claus V, Garg, Gagan, Peters, Timothy J, Kramer, Belinda A, Malani, Nirav V, Hyman, Jessica, Ruan, Xiaoan, Ginn, Samantha L, Hetherington, Nicola A, Veeravalli, Lavanya, Shahab, Atif, Ranganathan, Shoba, Wei, Chia-Lin, Liddle, Christopher, Thrasher, Adrian J, Bushman, Frederic D, Buckley, Michael J, Alexander, Ian E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445430/
https://ncbi.nlm.nih.gov/pubmed/26029726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2015.15
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados