Randomized phase III clinical trial comparing the combination of capecitabine and oxaliplatin (CAPOX) with the combination of 5-fluorouracil, leucovorin and oxaliplatin (modified FOLFOX6) as adjuvant therapy in patients with operated high-risk stage II or stage III colorectal cancer

BACKGROUND: The aim of the trial was to compare two active adjuvant chemotherapy regimens in patients with early stage colorectal cancer (CRC). METHODS: Patients were assigned to oxaliplatin, leucovorin and 5-FU for 12 cycles (group A, FOLFOX6) or oxaliplatin and capecitabine for eight cycles (group...

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Publicat a:BMC Cancer
Autors principals: Pectasides, Dimitrios, Karavasilis, Vasilios, Papaxoinis, George, Gourgioti, Georgia, Makatsoris, Thomas, Raptou, Georgia, Vrettou, Eleni, Sgouros, Joseph, Samantas, Epaminontas, Basdanis, George, Papakostas, Pavlos, Bafaloukos, Dimitrios, Kotoula, Vassiliki, Kalofonos, Haralambos P., Scopa, Chrisoula D., Pentheroudakis, George, Fountzilas, George
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445286/
https://ncbi.nlm.nih.gov/pubmed/25956750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1406-7
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