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Application of quantitative proteomics to the integrated analysis of the ubiquitylated and global proteomes of xenograft tumor tissues

BACKGROUND: Post-translational modification by ubiquitin is a fundamental regulatory mechanism that is implicated in many cellular processes including the cell cycle, apoptosis, cell adhesion, angiogenesis, and tumor growth. The low stoichiometry of ubiquitylation presents an analytical challenge fo...

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Detalhes bibliográficos
Publicado no:Clin Proteomics
Main Authors: Thomas, Stefani N, Zhang, Hui, Cotter, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445283/
https://ncbi.nlm.nih.gov/pubmed/26019700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12014-015-9086-5
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