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Thrombospondin peptide ABT-898 inhibits inflammation and angiogenesis in a colitis model

AIM: To evaluate the efficacy of the improved thrombospondin mimetic peptide ABT-898 in a murine model of ulcerative colitis. METHODS: The dextran sodium sulfate (DSS) was used for the induction of colitis in both TSP-1 deficient (TSP-1(-/-)) and wild type (WT) mice during 7 d. While mice were recei...

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Publicado en:World J Gastroenterol
Main Authors: Gutierrez, Linda S, Ling, Jun, Nye, Derek, Papathomas, Konstantina, Dickinson, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445093/
https://ncbi.nlm.nih.gov/pubmed/26034351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v21.i20.6157
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