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A transcription and translation-coupled DNA replication system using rolling-circle replication

All living organisms have a genome replication system in which genomic DNA is replicated by a DNA polymerase translated from mRNA transcribed from the genome. The artificial reconstitution of this genome replication system is a great challenge in in vitro synthetic biology. In this study, we attempt...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Sakatani, Yoshihiro, Ichihashi, Norikazu, Kazuta, Yasuaki, Yomo, Tetsuya
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445062/
https://ncbi.nlm.nih.gov/pubmed/26013404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10404
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