Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum

[Image: see text] Cyclotides are head-to-tail cyclized peptides comprising a stabilizing cystine-knot motif. To date, they are well known for their diverse bioactivities such as anti-HIV and immunosuppressive properties. Yet little is known about specific molecular mechanisms, in particular the inte...

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Опубликовано в: :J Nat Prod
Главные авторы: Hellinger, Roland, Koehbach, Johannes, Puigpinós, Albert, Clark, Richard J., Tarragó, Teresa, Giralt, Ernest, Gruber, Christian W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Chemical Society and American Society of Pharmacognosy 2015
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444998/
https://ncbi.nlm.nih.gov/pubmed/25894999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np501061t
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