Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology

Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues are largely uncharted. We analyzed 6,260 human piRNA transcriptomes derived from non-malignant and tumour tissues from 11 organs. We...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Martinez, Victor D., Vucic, Emily A., Thu, Kelsie L., Hubaux, Roland, Enfield, Katey S.S., Pikor, Larissa A., Becker-Santos, Daiana D., Brown, Carolyn J., Lam, Stephen, Lam, Wan L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444957/
https://ncbi.nlm.nih.gov/pubmed/26013764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10423
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