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An Investigation and Characterization on Alginate Hydogel Dressing Loaded with Metronidazole Prepared by Combined Inotropic Gelation and Freeze-Thawing Cycles for Controlled Release

The purpose of this study was to investigate the effect of combined Ca(2+) cross-linking and freeze-thawing cycle method on metronidazole (model drug) drug release and prepare a wound film dressing with improved swelling property. The hydrogel films were prepared with sodium alginate (SA) using the...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Sarheed, Omar, Abdul Rasool, Bazigha K., Abu-Gharbieh, Eman, Aziz, Uday Sajad
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444622/
https://ncbi.nlm.nih.gov/pubmed/25425388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0237-1
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