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5-Lipoxygenase, but Not 12/15-Lipoxygenase, Contributes to Degeneration of Retinal Capillaries in a Mouse Model of Diabetic Retinopathy
OBJECTIVE: Lipoxygenases are regulators of chronic inflamation and oxidative stress generation. We evaluated the role of 5-and 12-lipoxygenases in the development of diabetic retinopathy. RESEARCH DESIGN AND METHODS: Wild-type mice, 5-lipoxygenase– deficient mice, and 12/15-lipoxygenase– deficient m...
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| Pubblicato in: | Diabetes |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4444435/ https://ncbi.nlm.nih.gov/pubmed/18346986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db07-1217 |
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