A fluorescent bisboronic acid compound that selectively labels cells expressing oligosaccharide Lewis X

Two fluorescent diboronic acid compounds (6a and 6b) with a dipeptide linker were synthesized as potential sensors for cell surface saccharide Lewis X (Le(X)). Compound 6a with a dipeptide (H-Asp-Ala-) as the linker was found to selectively label CHOFUT4 cells, which express Le(x), at micromolar con...

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Detalhes bibliográficos
Publicado no:Bioorg Med Chem Lett
Main Authors: Gao, Xingming, Zhu, Mengyuan, Fan, Haiying, Yang, Wenqian, Ni, Weijuan, Karnati, Vishnu V. R., Gao, Shouhai, Carson, John, Weston, Brent, Wang, Binghe
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444404/
https://ncbi.nlm.nih.gov/pubmed/25956415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.04.069
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