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Delta frequency optogenetic stimulation of a thalamic nucleus reuniens is sufficient to produce working memory deficits; relevance to schizophrenia
BACKGROUND: Low-frequency (delta/theta) oscillations in the thalamocortical system are elevated in schizophrenia during wakefulness and are also induced in the NMDAR hypofunction rat model. To determine whether abnormal delta oscillations might produce functional deficits, we used optogenetic method...
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| Publicado no: | Biol Psychiatry |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4444380/ https://ncbi.nlm.nih.gov/pubmed/25891221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2015.01.020 |
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