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Metabolism of Penicillins to Penicilloic Acids and 6-Aminopenicillanic Acid in Man and Its Significance in Assessing Penicillin Absorption

Penicillins can be metabolized to penicilloic acids in man, the extent being dependent on the penicillin structure. In the phenoxy penicillin series, phenoxymethyl penicillin was found to be particularly unstable, but the higher homologues were more stable. In the isoxazolyl series, oxacillin was un...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Cole, M., Kenig, M. D., Hewitt, Valerie A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1973
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444435/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4364176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.3.4.463
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