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A human oncogene of the RAS superfamily unmasked by expression cDNA cloning.

As an approach to identify human oncogenes, we generated an expression cDNA library from an ovarian carcinoma line. A potent transforming gene was detected by transfection analysis and identified as TC21, a recently cloned member of the RAS gene superfamily. A single point mutation substituting glut...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chan, A M, Miki, T, Meyers, K A, Aaronson, S A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44441/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052619/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7558
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