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Increased Missense Mutation Burden of Fatty Acid Metabolism Related Genes in Nunavik Inuit Population

BACKGROUND: Nunavik Inuit (northern Quebec, Canada) reside along the arctic coastline where for generations their daily energy intake has mainly been derived from animal fat. Given this particular diet it has been hypothesized that natural selection would lead to population specific allele frequency...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Zhou, Sirui, Xiong, Lan, Xie, Pingxing, Ambalavanan, Amirthagowri, Bourassa, Cynthia V., Dionne-Laporte, Alexandre, Spiegelman, Dan, Turcotte Gauthier, Maude, Henrion, Edouard, Diallo, Ousmane, Dion, Patrick A., Rouleau, Guy A.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444093/
https://ncbi.nlm.nih.gov/pubmed/26010953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128255
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