Increased Missense Mutation Burden of Fatty Acid Metabolism Related Genes in Nunavik Inuit Population

BACKGROUND: Nunavik Inuit (northern Quebec, Canada) reside along the arctic coastline where for generations their daily energy intake has mainly been derived from animal fat. Given this particular diet it has been hypothesized that natural selection would lead to population specific allele frequency...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Zhou, Sirui, Xiong, Lan, Xie, Pingxing, Ambalavanan, Amirthagowri, Bourassa, Cynthia V., Dionne-Laporte, Alexandre, Spiegelman, Dan, Turcotte Gauthier, Maude, Henrion, Edouard, Diallo, Ousmane, Dion, Patrick A., Rouleau, Guy A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444093/
https://ncbi.nlm.nih.gov/pubmed/26010953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0128255
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