The c-kit ligand suppresses apoptosis of human natural killer cells through the upregulation of bcl-2.
The bcl-2 protein plays a central role in the regulation of programmed cell death in a variety of tissues and is pivotal to the survival of lymphocytes in vivo. The growth factors responsible for survival of normal lymphocytes are unknown but are likely to maintain viability in part through the regu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44440/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7519782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7553 |
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