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Comparison of the Chemotherapeutic and Pharmacodynamic Activities of Cephradine, Cephalothin, and Cephaloridine in Mice

Cephradine, a new semisynthetic cephalosporin derivative, is 7[d(−)-2-amino-2-(1,4-cyclohexadien-1-yl) acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrate. The compound has a broad spectrum of antimicrobial activity in vitro. When given subcutaneously to mice, cep...

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Main Authors: Miraglia, Gennaro J., Renz, Kathleen J., Gadebusch, Hans H.
Formato: Artigo
Idioma:Inglês
Publicado: 1973
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC444399/
https://ncbi.nlm.nih.gov/pubmed/4790592
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