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Regulation of α5 and αV Integrin Expression by GDF-5 and BMP-7 in Chondrocyte Differentiation and Osteoarthritis

The Integrin β1 family is the major receptors of the Extracellular matrix (ECM), and the synthesis and degradation balance of ECM is seriously disrupted during Osteoarthritis (OA). In this scenario, integrins modify their pattern expression and regulate chondrocyte differen-tiation in the articular...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garciadiego-Cázares, David, Aguirre-Sánchez, Hilda I., Abarca-Buis, René F., Kouri, Juan B., Velasquillo, Cristina, Ibarra, Clemente
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443976/
https://ncbi.nlm.nih.gov/pubmed/26010756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127166
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