XRCC5 as a Risk Gene for Alcohol Dependence: Evidence from a Genome-Wide Gene-Set-Based Analysis and Follow-up Studies in Drosophila and Humans

Genetic factors have as large role as environmental factors in the etiology of alcohol dependence (AD). Although genome-wide association studies (GWAS) enable systematic searches for loci not hitherto implicated in the etiology of AD, many true findings may be missed owing to correction for multiple...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Juraeva, Dilafruz, Treutlein, Jens, Scholz, Henrike, Frank, Josef, Degenhardt, Franziska, Cichon, Sven, Ridinger, Monika, Mattheisen, Manuel, Witt, Stephanie H, Lang, Maren, Sommer, Wolfgang H, Hoffmann, Per, Herms, Stefan, Wodarz, Norbert, Soyka, Michael, Zill, Peter, Maier, Wolfgang, Jünger, Elisabeth, Gaebel, Wolfgang, Dahmen, Norbert, Scherbaum, Norbert, Schmäl, Christine, Steffens, Michael, Lucae, Susanne, Ising, Marcus, Smolka, Michael N, Zimmermann, Ulrich S, Müller-Myhsok, Bertram, Nöthen, Markus M, Mann, Karl, Kiefer, Falk, Spanagel, Rainer, Brors, Benedikt, Rietschel, Marcella
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443948/
https://ncbi.nlm.nih.gov/pubmed/25035082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2014.178
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