Effect of 1-β-d-Ribofuranosyl-1,2,4-Triazole-3-Carboxamide (Virazole, ICN 1229) on Herpes and Vaccinia Keratitis and Encephalitis in Laboratory Animals

Topical application of 1-β-d-ribofuranosyl-1,2,4-triazole-3-carboxamide (Virazole) significantly inhibited the development of herpetic keratitis in the eyes of rabbits, as determined by both infectivity and Draize scoring parameters. Significant inhibition of the infection was demonstrated with 10%...

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Bibliografiska uppgifter
Huvudupphovsmän: Sidwell, Robert W., Allen, Lois B., Khare, G. P., Huffman, John H., Witkowski, J. T., Simon, Lionel N., Robins, Roland K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1973
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC444394/
https://ncbi.nlm.nih.gov/pubmed/4790589
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