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Studies on the Toxicity and Antiviral Activity of Various Polynucleotides

Various polynucleotides were examined for antiviral activity and toxicity in mice. Although the antiviral potency of the various interferon inducers varied, there was a concomitant variation in toxicity. This was reflected by a fivefold range in therapeutic ratio for the various compounds. In additi...

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Detalhes bibliográficos
Main Authors: Black, D. R., Eckstein, F., DeClercq, E., Merigan, T. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444387/
https://ncbi.nlm.nih.gov/pubmed/4790587
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