Translational toxicology in setting occupational exposure limits for dusts and hazard classification – a critical evaluation of a recent approach to translate dust overload findings from rats to humans

BACKGROUND: We analyze the scientific basis and methodology used by the German MAK Commission in their recommendations for exposure limits and carcinogen classification of “granular biopersistent particles without known specific toxicity” (GBS). These recommendations are under review at the European...

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Detalhes bibliográficos
Publicado no:Part Fibre Toxicol
Main Authors: Morfeld, Peter, Bruch, Joachim, Levy, Len, Ngiewih, Yufanyi, Chaudhuri, Ishrat, Muranko, Henry J, Myerson, Ross, McCunney, Robert J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443602/
https://ncbi.nlm.nih.gov/pubmed/25925672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-015-0079-3
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