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Muscular forces affect the glycosaminoglycan content of joint cartilage: Unloading in human volunteers with the HEPHAISTOS lower leg orthosis

BACKGROUND AND PURPOSE: Unloading alters the thickness of joint cartilage. It is unknown, however, to what extent unloading leads to a loss of glycosaminoglycans (GAGs) in the cartilage tissue. We hypothesized that muscle forces, in addition to axial loading, are necessary to maintain the joint cart...

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Detalhes bibliográficos
Publicado no:Acta Orthop
Main Authors: Ganse, Bergita, Zange, Jochen, Weber, Tobias, Pohle-Fröhlich, Regina, Johannes, Bernd W, Hackenbroch, Matthias, Rittweger, Jörn, Eysel, Peer, Koy, Timmo
Formato: Artigo
Idioma:Inglês
Publicado em: Informa Healthcare 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443457/
https://ncbi.nlm.nih.gov/pubmed/25417835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/17453674.2014.989382
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