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Chondroprotective effects of Salubrinal in a mouse model of osteoarthritis

OBJECTIVES: Salubrinal is a synthetic agent that elevates phosphorylation of eukaryotic translation initiation factor 2 alpha (eIF2α) and alleviates stress to the endoplasmic reticulum. Previously, we reported that in chondrocytes, Salubrinal attenuates expression and activity of matrix metalloprote...

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發表在:Bone Joint Res
Main Authors: Hamamura, K., Nishimura, A., Iino, T., Takigawa, S., Sudo, A., Yokota, H.
格式: Artigo
語言:Inglês
出版: British Editorial Society of Bone and Joint Surgery 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443296/
https://ncbi.nlm.nih.gov/pubmed/25977571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1302/2046-3758.45.2000378
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