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Global deletion of MGL in mice delays lipid absorption and alters energy homeostasis and diet-induced obesity

Monoacylglycerol lipase (MGL) is a ubiquitously expressed enzyme that catalyzes the hydrolysis of monoacylglycerols (MGs) to yield FFAs and glycerol. MGL contributes to energy homeostasis through the mobilization of fat stores and also via the degradation of the endocannabinoid 2-arachidonoyl glycer...

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Bibliographic Details
Published in:J Lipid Res
Main Authors: Douglass, John D., Zhou, Yin Xiu, Wu, Amy, Zadrogra, John A., Gajda, Angela M., Lackey, Atreju I., Lang, Wensheng, Chevalier, Kristen M., Sutton, Steven W., Zhang, Sui-Po, Flores, Christopher M., Connelly, Margery A., Storch, Judith
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442873/
https://ncbi.nlm.nih.gov/pubmed/25842377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M058586
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