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Flexibility of Bunyavirus Genomes: Creation of an Orthobunyavirus with an Ambisense S Segment

The Bunyamwera (BUNV) orthobunyavirus NSs protein has proven a challenge to study in the context of viral infection. NSs is encoded in a reading frame that overlaps that of the viral nucleocapsid (N) protein thus limiting options for mutagenesis. In addition, NSs is poorly immunogenic, and antibodie...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: van Knippenberg, Ingeborg, Elliott, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442540/
https://ncbi.nlm.nih.gov/pubmed/25740985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03595-14
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