Function of the Herpes Simplex Virus 1 Small Capsid Protein VP26 Is Regulated by Phosphorylation at a Specific Site

Replacement of the herpes simplex virus 1 small capsid protein VP26 phosphorylation site Thr-111 with alanine reduced viral replication and neurovirulence to levels observed with the VP26 null mutation. This mutation reduced VP26 expression and mislocalized VP26 and its binding partner, the major ca...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Kobayashi, Ryosuke, Kato, Akihisa, Oda, Shinya, Koyanagi, Naoto, Oyama, Masaaki, Kozuka-Hata, Hiroko, Arii, Jun, Kawaguchi, Yasushi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442450/
https://ncbi.nlm.nih.gov/pubmed/25810545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00547-15
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