Function of the Herpes Simplex Virus 1 Small Capsid Protein VP26 Is Regulated by Phosphorylation at a Specific Site

Replacement of the herpes simplex virus 1 small capsid protein VP26 phosphorylation site Thr-111 with alanine reduced viral replication and neurovirulence to levels observed with the VP26 null mutation. This mutation reduced VP26 expression and mislocalized VP26 and its binding partner, the major ca...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kobayashi, Ryosuke, Kato, Akihisa, Oda, Shinya, Koyanagi, Naoto, Oyama, Masaaki, Kozuka-Hata, Hiroko, Arii, Jun, Kawaguchi, Yasushi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442450/
https://ncbi.nlm.nih.gov/pubmed/25810545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00547-15
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