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A Japanese Encephalitis Virus Genotype 5 Molecular Clone Is Highly Neuropathogenic in a Mouse Model: Impact of the Structural Protein Region on Virulence

Japanese encephalitis virus (JEV) strains can be separated into 5 genotypes (g1 to g5) based on sequence similarity. JEV g5 strains have been rarely isolated and are poorly characterized. We report here the full characterization of a g5 virus generated using a cDNA-based technology and its compariso...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: de Wispelaere, Mélissanne, Frenkiel, Marie-Pascale, Desprès, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442416/
https://ncbi.nlm.nih.gov/pubmed/25787283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00358-15
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