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Oxidative Stress and Protein Quality Control Systems in the Aged Canine Brain as a Model for Human Neurodegenerative Disorders

Aged dogs are considered the most suitable spontaneous animal model for studying normal aging and neurodegenerative diseases. Elderly canines naturally develop cognitive dysfunction and neuropathological hallmarks similar to those seen in humans, especially Alzheimer's disease-like pathology. P...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Romanucci, Mariarita, Della Salda, Leonardo
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442305/
https://ncbi.nlm.nih.gov/pubmed/26078824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/940131
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