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Oxidative Stress and Protein Quality Control Systems in the Aged Canine Brain as a Model for Human Neurodegenerative Disorders

Aged dogs are considered the most suitable spontaneous animal model for studying normal aging and neurodegenerative diseases. Elderly canines naturally develop cognitive dysfunction and neuropathological hallmarks similar to those seen in humans, especially Alzheimer's disease-like pathology. P...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Romanucci, Mariarita, Della Salda, Leonardo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442305/
https://ncbi.nlm.nih.gov/pubmed/26078824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/940131
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