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SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

Smc–ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic basis for its action, however, is only poorly understood. Here, we have established a physical assay to determine whether the binding of con...

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Detalhes bibliográficos
Publicado no:eLife
Principais autores: Wilhelm, Larissa, Bürmann, Frank, Minnen, Anita, Shin, Ho-Chul, Toseland, Christopher P, Oh, Byung-Ha, Gruber, Stephan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442127/
https://ncbi.nlm.nih.gov/pubmed/25951515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.06659
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