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Time to prerandomization monthly seizure count in perampanel trials: A novel epilepsy endpoint

OBJECTIVE: To determine whether a novel endpoint of time to prerandomization monthly seizure count could be used to differentiate efficacious and nonefficacious therapies in clinical trials of new add-on antiepileptic drugs (AEDs). METHODS: This analysis used data from 3 randomized, double-blind, pl...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: French, Jacqueline A., Gil-Nagel, Antonio, Malerba, Stefano, Kramer, Lynn, Kumar, Dinesh, Bagiella, Emilia
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442101/
https://ncbi.nlm.nih.gov/pubmed/25878175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001585
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