Detection of a Cephalosporin C Acetyl Esterase in the Carbamate Cephalosporin Antibiotic-Producing Culture, Streptomyces clavuligerus

The possible role of a cephalosporin C acetyl esterase in the formation of the β-lactam antibiotic A16886A, 7-(5-amino-5-carboxyvaleramido)-3-carbamoyloxy-methyl-3-cephem-4-carboxylic acid, by Streptomyces clavuligerus was studied. Addition of dl-valine-(14)C-1 to a fermentation of Cephalosporium ac...

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Autores principales: Brannon, D. R., Fukuda, D. S., Mabe, J. A., Huber, F. M., Whitney, J. G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1972
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC444198/
https://ncbi.nlm.nih.gov/pubmed/5045469
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