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Deletion of UNC5B in kidney epithelium exacerbates diabetic nephropathy in mice

BACKGROUND: Guidance cue netrin-1 was shown to have protective effects in diabetic nephropathy. However, the role of its receptor UNC5B in diabetic kidney disease is unknown. Moreover, whether netrin-1 is protective against diabetic kidney disease in a genetic model of nephropathy and in the nephrop...

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Detalhes bibliográficos
Publicado no:Am J Nephrol
Main Authors: Ranganathan, Punithavathi, Mohamed, Riyaz, Jayakumar, Calpurnia, Brands, Michael W., Ramesh, Ganesan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441848/
https://ncbi.nlm.nih.gov/pubmed/25896231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000381428
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