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Endothelial epigenetics in biomechanical stress: Disturbed flow-mediated epigenomic plasticity in vivo and in vitro

Arterial endothelial phenotype is regulated by local hemodynamic forces that are linked to regional susceptibility to atherogenesis. A complex hierarchy of transcriptional, translational and posttranslational mechanisms are greatly influenced by the characteristics of local arterial shear stress env...

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Détails bibliographiques
Publié dans:Arterioscler Thromb Vasc Biol
Auteurs principaux: Jiang, Yi-Zhou, Manduchi, Elisabetta, Jiménez, Juan M., Davies, Peter F.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441576/
https://ncbi.nlm.nih.gov/pubmed/25838424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.303427
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