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Mild heat treatment primes human CD34(+) cord blood cells for migration towards SDF-1α and enhances engraftment in an NSG mouse model
Simple efforts are needed to enhance cord blood (CB) transplantation. We hypothesized that short-term exposure of CD34(+) CB cells to 39.5°C would enhance their response to SDF-1, by increasing lipid raft aggregation and CXCR4 expression, thus leading to enhanced engraftment. Mild hyperthermia (39.5...
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| 出版年: | Stem Cells |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4441568/ https://ncbi.nlm.nih.gov/pubmed/25753525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1988 |
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