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Antigen-Specific Blocking of CD4-Specific Immunological Synapse Formation Using BPI and Current Therapies for Autoimmune Diseases

In this review, we discuss T-cell activation, etiology, and the current therapies of autoimmune diseases (i.e., MS, T1D, and RA). T-cells are activated upon interaction with antigen-presenting cells (APC) followed by a “bull’s eye”-like formation of the immunological synapse (IS) at the T-cell–APC i...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Med Res Rev
Päätekijät: Manikwar, Prakash, Kiptoo, Paul, Badawi, Ahmed H., Büyüktimkin, Barlas, Siahaan, Teruna J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441537/
https://ncbi.nlm.nih.gov/pubmed/21433035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/med.20243
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