MAGE-A Cancer/Testis Antigens Inhibit MDM2 Ubiquitylation Function and Promote Increased Levels of MDM4

Melanoma antigen A (MAGE-A) proteins comprise a structurally and biochemically similar sub-family of Cancer/Testis antigens that are expressed in many cancer types and are thought to contribute actively to malignancy. MAGE-A proteins are established regulators of certain cancer-associated transcript...

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Foilsithe in:PLoS One
Main Authors: Marcar, Lynnette, Ihrig, Bianca, Hourihan, John, Bray, Susan E., Quinlan, Philip R., Jordan, Lee B., Thompson, Alastair M., Hupp, Ted R., Meek, David W.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2015
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441487/
https://ncbi.nlm.nih.gov/pubmed/26001071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127713
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