Molecular Confirmation of t(6;11)(p21;q12) Renal Cell Carcinoma in Archival Paraffin-embedded Material Using a Break-apart TFEB FISH Assay Expands its Clinicopathologic Spectrum

A subset of renal cell carcinomas (RCCs) is characterized by t(6;11)(p21;q12), which results in fusion of the untranslated Alpha (MALAT1) gene to the TFEB gene. Only 21 genetically confirmed cases of t(6;11) RCCs have been reported. This neoplasm typically demonstrates a distinctive biphasic morphol...

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Detalhes bibliográficos
Publicado no:Am J Surg Pathol
Main Authors: Argani, Pedram, Yonescu, Raluca, Morsberger, Laura, Morris, Kerry, Netto, George J., Smith, Nathan, Gonzalez, Nilda, Illei, Peter B., Ladanyi, Marc, Griffin, Constance A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441265/
https://ncbi.nlm.nih.gov/pubmed/22892601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0b013e3182613d8f
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