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Clustering and Negative Feedback by Endocytosis in Planar Cell Polarity Signaling Is Modulated by Ubiquitinylation of Prickle

The core components of the planar cell polarity (PCP) signaling system, including both transmembrane and peripheral membrane associated proteins, form asymmetric complexes that bridge apical intercellular junctions. While these can assemble in either orientation, coordinated cell polarization requir...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Cho, Bomsoo, Pierre-Louis, Gandhy, Sagner, Andreas, Eaton, Suzanne, Axelrod, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440771/
https://ncbi.nlm.nih.gov/pubmed/25996914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005259
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