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Estrogen receptor-α signaling and localization regulates autophagy and unfolded protein response activation in ER+ breast cancer
Antiestrogen therapy is commonly used to treat estrogen receptor (ER)+ breast cancers but acquired and de novo resistance limits their overall curative potential. An endoplasmic reticulum stress pathway, the unfolded protein response, and autophagy are both implicated in the development of antiestro...
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| Опубликовано в: : | Receptors Clin Investig |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440691/ https://ncbi.nlm.nih.gov/pubmed/26005699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/rci.316 |
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