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The role of antigen specificity in the binding of murine monoclonal anti-DNA antibodies to microparticles from apoptotic cells

Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus and markers of underlying immune system disturbances. These antibodies bind to both single-stranded and double-stranded DNA, mediating pathogenesis by forming immune complexes. As shown recently, DNA in blood e...

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Detalhes bibliográficos
Publicado no:Clin Immunol
Main Authors: Ullal, Anirudh J., Marion, Tony N., Pisetsky, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440675/
https://ncbi.nlm.nih.gov/pubmed/24873886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.05.007
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