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The role of antigen specificity in the binding of murine monoclonal anti-DNA antibodies to microparticles from apoptotic cells
Antibodies to DNA (anti-DNA) are the serological hallmark of systemic lupus erythematosus and markers of underlying immune system disturbances. These antibodies bind to both single-stranded and double-stranded DNA, mediating pathogenesis by forming immune complexes. As shown recently, DNA in blood e...
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| Published in: | Clin Immunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4440675/ https://ncbi.nlm.nih.gov/pubmed/24873886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2014.05.007 |
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