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A mechanism of nucleocytoplasmic trafficking for the homeodomain protein PRH

PRH/Hex is a homeodomain protein that plays an important role in early embryonic patterning and hematopoiesis. PRH can act as either a tumor suppressor or an oncogene and its expression is dysregulated in certain types of lymphoid and myeloid leukemias. Aberrant exclusion of PRH from the nuclei has...

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Detalhes bibliográficos
Publicado no:Mol Cell Biochem
Main Authors: Ploski, Jonathan E., Topisirovic, Ivan, Park, Kevin W., Borden, Katherine L. B., Radu, Aurelian
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440652/
https://ncbi.nlm.nih.gov/pubmed/19588232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0188-0
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