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Regulators Associated with Clinical Outcomes Revealed by DNA Methylation Data in Breast Cancer

The regulatory architecture of breast cancer is extraordinarily complex and gene misregulation can occur at many levels, with transcriptional malfunction being a major cause. This dysfunctional process typically involves additional regulatory modulators including DNA methylation. Thus, the interplay...

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Bibliographic Details
Published in:PLoS Comput Biol
Main Authors: Ung, Matthew H., Varn, Frederick S., Lou, Shaoke, Cheng, Chao
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440643/
https://ncbi.nlm.nih.gov/pubmed/25996148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004269
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