IGFBP-5 Metabolism Is Disrupted in the Rat Medial Meniscal Tear Model of Osteoarthritis

Insulin-like growth factor binding protein 5 (IGFBP-5) has been proposed to promote cartilage anabolism through insulin-like growth factor (IGF-1) signaling. A proteolytic activity towards IGFBP-5 has been detected in synovial fluids from human osteoarthritic (OA) joints. The purpose of this study w...

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Detalhes bibliográficos
Publicado no:Cartilage
Main Authors: Yates, Matthew P., Settle, Steven L., Yocum, Sue A., Aggarwal, Poonam, Vickery, Lillian E., Aguiar, Dean J., Skepner, Adam P., Kellner, Debra, Weinrich, Scott L., Sverdrup, Francis M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440612/
https://ncbi.nlm.nih.gov/pubmed/26069535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947603509359189
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