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Development and molecular characterization of polymeric micro-nanofibrous scaffold of a defined 3-D niche for in vitro chemosensitivity analysis against acute myeloid leukemia cells

Standard in vitro drug testing employs 2-D tissue culture plate systems to test anti-leukemic drugs against cell adhesion-mediated drug-resistant leukemic cells that harbor in 3-D bone marrow microenvironments. This drawback necessitates the fabrication of 3-D scaffolds that have cell adhesion-media...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Nair, Maya S, Mony, Ullas, Menon, Deepthy, Koyakutty, Manzoor, Sidharthan, Neeraj, Pavithran, Keechilat, Nair, Shantikumar V, Menon, Krishnakumar N
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4440427/
https://ncbi.nlm.nih.gov/pubmed/26028971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S80397
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