Effect of oral administration of kynurenic acid on the activity of the peripheral blood leukocytes in mice

Kynurenic acid (KYNA), an endogenous tryptophan metabolite, is a selective ligand of the GPR35 receptor, expressed mainly on the immune cells. In inflammatory conditions, by affecting this receptor, KYNA inhibits the synthesis of pro-inflammatory cytokines and probably protects tissues from oxidativ...

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Detalhes bibliográficos
Publicado no:Cent Eur J Immunol
Main Authors: Małaczewska, Joanna, Siwicki, Andrzej Krzysztof, Wójcik, Roman Marcin, Kaczorek, Edyta, Turski, Waldemar Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: Polish Society of Experimental and Clinical Immunology 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439973/
https://ncbi.nlm.nih.gov/pubmed/26155092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/ceji.2014.42115
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