DHEA modulates the effect of cortisol on RACK1 expression via interference with the splicing of the glucocorticoid receptor

BACKGROUND AND PURPOSE: Dehydroepiandrosterone (DHEA) is thought to be an anti-glucocorticoid hormone known to be fully functional in young people but deficient in aged humans. Our previous data suggest that DHEA not only counteracts the effect of cortisol on RACK1 expression, a protein required bot...

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發表在:Br J Pharmacol
Main Authors: Pinto, Antonella, Malacrida, Beatrice, Oieni, Jacopo, Serafini, Melania Maria, Davin, Annalisa, Galbiati, Valentina, Corsini, Emanuela, Racchi, Marco
格式: Artigo
語言:Inglês
出版: BlackWell Publishing Ltd 2015
主題:
Research Papers
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439885/
https://ncbi.nlm.nih.gov/pubmed/25626076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13097
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