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The endoplasmic reticulum stress and the HIF-1 signalling pathways are involved in the neuronal damage caused by chemical hypoxia

BACKGROUND AND PURPOSE: Hypoxia inducible factor-1 (HIF-1) promotes transitory neuronal survival suggesting that additional mechanisms such as the endoplasmic reticulum (ER) stress might be involved in determining neuronal survival or death. Here, we examined the involvement of ER stress in hypoxia-...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: López-Hernández, Beatriz, Ceña, Valentin, Posadas, Inmaculada
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4439879/
https://ncbi.nlm.nih.gov/pubmed/25625917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13095
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